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Vitamin C and E supplements may make lung cancers grow faster

Supplementing with antioxidants such as vitamins C and E could increase the formation of blood vessels within lung cancer tumours, helping them to grow bigger and spread, according to a study in mice. Taking antioxidant supplements such as vitamins C and E may cause lung cancers to grow bigger and spread by stimulating the formation of blood vessels within tumours, according to a study in mice. One researcher has stressed that people with the condition shouldn’t try to avoid these antioxidants in their diet, but getting more than they need via supplements could cause harm. Martin Bergö at the Karolinska Institute in Sweden and his colleagues previously found that supplementing with the antioxidants vitamin E and n-acetylcysteine caused lung cancers to spread in mice. To better understand how this might occur, Bergö and a new team of researchers studied mice with a murine-specific form of lung cancer and mice that had been implanted with human lung cancer cells. They supplemented the mice’s water with vitamin C, which the animals naturally produce, and vitamin E and n-acetylcysteine, which they get from their diet. These supplements were administered at increasing doses, all of which caused the mice’s levels of these antioxidants to exceed what was necessary. “Today in society, you have a lot of people who eat healthily, they have some supplements, and then they may have a ginger shot and a smoothie,” says Bergö. “If you do all that, you could end up with the levels of doses that we’re talking about.”

  • 4 September, 10:28
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Working nights leads to a higher chance of memory loss, experts warn

People on the night shift may run a greater risk of memory loss compared to those takin’ care of business during the day, a new study has shown. Researchers at York University in Canada found that those working shifts outside the average 9 a.m. to 5 p.m. schedule were more prone to suffer from cognitive impairments, such as inability to think clearly, brain deterioration and behavioral changes. The study, which gathered data on 47,811 adults and analyzed self-reported employment information alongside the results of cognitive function tests, was published this week in the open-access journal PLOS ONE. “Findings suggest a potential link between shift work exposure and cognitive function impairment,” the experts concluded. Working nights could lead to memory loss in middle-aged and older adults as those working late have 79% higher rates of cognitive impairment. And while the overnighters may have been more likely to suffer from issues with memory, those on more regular hours were more likely to struggle with the ability to manage their own thoughts, emotions and actions. Nearly one in five individuals (21%) are likely to engage in shift work during their careers. The experts suggest that the disruption to a person’s circadian rhythm caused by shift work is likely causing these detrimental impacts to people’s cognitive function, especially in middle-aged and older adults. Every cell in the body operates on a circadian clock, an internally driven 24-hour rhythm that often runs longer than 24 hours. It resets every day by the sun’s cycle but can be disrupted by too much or too little sunlight exposure — a common issue for shift workers. A person’s circadian clock sets the timing for many important bodily functions including sleep cycles, hormonal activity, body temperature rhythm, eating and digesting.  Every adult should be tucking themselves in for at least seven hours a night, according to the Centers for Disease Control and Prevention. It’s estimated that nearly half of Americans are sleep-deprived. Offsetting the body’s circadian rhythm has been associated with a higher risk of a multitude of health issues including chronic diseases, depression, obesity, Type 2 diabetes, cardiovascular problems and headache disorders.

  • 29 August, 19:53
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The Global Pharmaceutical Leaders’ Club invites you for the 4th Eurasian Pharmaceutical Summit, which will be held with the support of the Pharmaceutical Industry Development Agency of the Ministry of Investment

The Global Pharmaceutical Leaders’ Club invites you for the 4th Eurasian Pharmaceutical Summit, which will be held with the support of the Pharmaceutical Industry Development Agency of the Ministry of Investment, Industry and Trade of the Republic of Uzbekistan. The summit will be held in a hybrid format on the 26th - 28th September with an offline part in Samarkand. This is the only conference that comprehensively covers the development trends in the pharmaceutical markets of the countries in Central Asia, the Caucasus and Eastern Europe. In an offline format the summit will bring together 250+ leading pharmaceutical market professionals from 10 countries and 100+ speakers from regulatory authorities, pharmaceutical manufacturing companies, distributors and pharmacy chains. The summit programme includes 20+ sessions, where the issues of market access, registration of pharmaceutical drugs, public procurement, labelling, pricing, sales, marketing and production of medicines will be discussed. There will be round tables with regulators and one-to-one meetings with top managers of leading pharmaceutical companies. For the first time, within the framework of the summit, visits to pharmaceutical drug distribution centres and manufacturing enterprises in Samarkand will be organised. As a part of the Eurasian Pharmaceutical Summit, the Eurasian Pharma Awards competition will be held for the 4th time. International and local pharmaceutical drug manufacturers, distributors and pharmacy chains are invited to participate. Details about the summit are on the website: https://eurasianpharmasummit.com/en/. 

  • 16 August, 08:56
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